- [Resource Hub](/) - [Field Guide](/?resource-type=field-guide#library) - The Unknown Product: Most Moxi Users Don't Know This Exists # The Unknown Product: Most Moxi Users Don't Know This Exists The Bottom Line Up Front: Most of the issue with viability reagents is that most people don't even know they exist. If you're running viability assays on Moxi V or Moxi GO II with generic dyes you optimized yourself, there's a better option you may not have heard about: pre-optimized, ready-to-use viability reagents designed specifically for your instrument. Now you know. ## The Awareness Gap There's no mystery about why people use generic viability dyes. They know generic dyes exist. They may not know optimized alternatives exist. Most people don't even know viability reagents are available. It's not that customers evaluated the options and chose generic - they just weren't aware there was a choice. When we emailed current customers to let them know viability reagents were available, we saw a distinctive uptick in orders. The demand was there; the awareness wasn't. ### TL;DR - Product Awareness Essentials - PCS Viability Reagents exist and are specifically formulated for Moxi V and Moxi GO II - Most customers simply don't know this product is available - When customers learn about optimized reagents, they often switch immediately - Pre-diluted, pre-optimized, ready-to-use - no customer optimization required - The product exists. The question is whether you knew about it until now ## What You Might Have Missed Discover the pre-optimized viability reagents available for your Moxi instrument. What You're Missing What You're Currently Missing + If you're using generic viability dyes, here's what you're doing without: Pre-optimization: Generic dyes require you to find the right concentration and incubation conditions. Optimized reagents deliver that optimization pre-done. Pre-dilution: Generic dyes come as concentrates requiring dilution. Optimized reagents are ready-to-use - already pre-diluted. Instrument matching: Generic dyes are generic - not optimized for any particular detection system. PCS reagents are formulated for Moxi V and GO II fluorescence detection. Clear instructions: Generic dyes come with generic guidance. Optimized reagents come with concentration-based instructions specific to your sample preparation. Who This Is For Who This Is For + PCS Viability Reagents are relevant to: Existing Moxi V users: If you're running viability assays with generic dyes, optimized reagents provide an immediate upgrade path. Existing Moxi GO II users: Same benefit - validated reagents that work with your instrument's detection system. New instrument adopters: If you just got a Moxi V or GO II, starting with optimized reagents means never going through the optimization process. Anyone tired of optimization: If protocol development feels like wasted time, pre-optimized reagents convert that overhead into productive work. The Moxi Z Question The Moxi Z Question + An important note: viability reagents are for Moxi V and Moxi GO II only. Moxi Z uses Coulter principle detection without fluorescence capability. If you have a Moxi Z, viability assessment requires different approaches - not fluorescent dyes. The Moxi V and GO II add fluorescence detection that enables viability dye assessment. Knowing what products exist for which instruments is part of getting the most from your equipment. Instrument Compatibility Viability reagents require fluorescence detection. Moxi Z uses Coulter principle only. Moxi V and GO II have both Coulter and fluorescence capabilities. Customer Response What Customers Say When They Find Out + The response to awareness is typically immediate interest: "Why didn't I know about this?" - The most common reaction. There's no good reason not to know; the product just wasn't on the radar. "How soon can I get it?" - Once customers understand the optimization burden they can eliminate, they want to make the switch. "Does it work with my cells?" - Yes. Pre-optimized reagents work across cell types compatible with Moxi instruments. The email campaigns proved it: tell customers this exists, and they buy it. The product delivers on what researchers want; they just needed to know it was available. Making the Switch Making the Switch + Transitioning from generic dyes to optimized reagents is straightforward: No revalidation required: The reagents are already validated for Moxi instruments. Simple protocol switch: Follow the concentration-based instructions. Put X amount of viability reagent, put X amount of sample, incubate and go. Immediate time savings: No more optimization experiments, titration curves, or protocol troubleshooting. Consistent results: Same performance every time, without user-dependent variation. ## Troubleshooting Guide Problem: Using generic viability dyes because I didn't know alternatives existed Now you know. PCS Viability Reagents are pre-optimized for Moxi V and GO II. No optimization required - order directly from Precision Cell Systems. Problem: Assumed optimized reagents would be too expensive Factor in your optimization time cost. Hours of protocol development have value. Pre-optimized reagents often provide better ROI when total cost is calculated. Problem: Not sure if this applies to my Moxi model Viability reagents work with Moxi V and Moxi GO II (instruments with fluorescence detection). Not applicable for Moxi Z. Problem: My lab already has a protocol with generic dyes Consider running a comparison. Pre-optimized reagents may provide better results with less variability - worth validating against your current protocol. ## Frequently Asked Questions Does Moxi have optimized viability reagents? Yes. PCS Viability Reagents are specifically formulated for Moxi V and Moxi GO II. They're pre-diluted and pre-optimized for these instruments - no customer optimization required. Most customers simply don't know these exist as an option. Why don't most customers know about viability reagents? Most of the issue is that most people don't even know they exist. They've never been told about them. When customers are informed that optimized reagents are available, they often purchase them immediately. Are optimized viability reagents worth the cost over generic dyes? Consider the hidden costs of generic dyes: optimization time, protocol development, inconsistent results, troubleshooting. Pre-optimized reagents eliminate these costs. Like buying pre-cast gels instead of pouring your own - the convenience and consistency justify the investment. How do I get viability reagents for my Moxi? PCS Viability Reagents can be ordered directly through Precision Cell Systems. They're available for Moxi V and Moxi GO II users. Contact us or visit our website to order pre-optimized viability reagents for your instrument. ### Key Takeaway The product exists. Pre-optimized viability reagents for Moxi V and Moxi GO II - ready to use, no optimization required. Most customers simply don't know about them. Now you do. The question isn't whether these reagents are better than optimizing generic dyes yourself; the question is whether you're going to keep doing things the hard way now that you know an easier option is available. [Back to all resources](/#library) ## Similar resources [Field Guide](/resources/01-optimization-burden/) Moxi GO II Moxi V 2026 ### The Optimization Burden: Hours Wasted on Viability Protocol Development Every hour spent optimizing viability dye concentrations is an hour not spent on your actual experiments. It's optimized for use - that's the important thing. You don't have to optimize it as a customer. Pre-optimized viability reagents eliminate the titration experiments, the incubation testing, the cell-type-specific protocol development. Why spend time optimizing when validated performance is available from the first use? [Read Field Guide](/resources/01-optimization-burden/) [Field Guide](/resources/04-protocol-hunt/) Moxi GO II Moxi V 2026 ### The Protocol Hunt: Searching for Methods That Already Exist Searching for viability protocols, adapting literature methods, trial-and-error until something works - this is time you don't need to spend. The user manual is designed to be super easy. Concentration-based instructions tell you exactly what to do: put X amount of viability reagent and put X amount of sample, incubate and go. No protocol hunting required. [Read Field Guide](/resources/04-protocol-hunt/) [Field Guide](/resources/05-diy-mentality/) Moxi GO II Moxi V 2026 ### The DIY Mentality: When Making Your Own Viability Reagent No Longer Makes Sense That's why people - including me - just buy premixed gel loading dye and don't make my own from powder like my PI wanted me to. The same logic applies to viability reagents. Buy the damn gels rather than making them - consistency and data. When convenience and consistency matter more than tradition, pre-made beats DIY. [Read Field Guide](/resources/05-diy-mentality/) [Field Guide](/resources/06-batch-consistency/) Moxi GO II Moxi V 2026 ### Viability Reagent Batch-to-Batch Consistency: Why Your Results Vary Over Time When you make your own viability reagents, every batch is different. When you buy pre-optimized reagents with QC'd lot consistency, every lot performs the same. Long-term experiments need long-term consistency - and that consistency comes from manufacturing quality control, not from hoping your technique stays identical over months of work. [Read Field Guide](/resources/06-batch-consistency/) [Field Guide](/resources/07-training-new-users/) Moxi GO II Moxi V 2026 ### Training New Users: Why Pre-Optimized Reagents Simplify Onboarding New lab members need to generate valid data quickly. Teaching protocol optimization takes weeks. Teaching protocol execution takes minutes. The user manual is designed to be super easy - put X amount of viability reagent, put X amount of sample, incubate and go. When reagents are pre-optimized, training focuses on execution, not development. [Read Field Guide](/resources/07-training-new-users/) [Field Guide](/resources/06-fifteen-micron-boundary/) Moxi GO II Moxi V Moxi Z 2026 ### The 15-Micrometer Decision: A Practical Cassette Selection Framework The 15 μm boundary provides clear selection criterion: cells under 15 micrometers use S+ cassettes, cells over 15 micrometers use M+ cassettes. This boundary isn't arbitrary - it's where each aperture size achieves the optimal 15-40% cell-to-aperture ratio for signal quality and sizing resolution. Know your cell size, follow the boundary, and cassette selection becomes automatic. [Read Field Guide](/resources/06-fifteen-micron-boundary/) [Field Guide](/resources/03-mixed-population-dilemma/) Moxi GO II Moxi V Moxi Z 2026 ### The Mixed Population Dilemma: When One Cassette Can't Capture Everything When your sample contains both small and large cells, no single cassette optimizes measurement for both populations. The solution: run the same sample twice - once with S+ to get accurate small cell counts, once with M+ to get accurate large cell counts. This dual-cassette workflow delivers accurate data for both populations rather than compromised data for everyone. [Read Field Guide](/resources/03-mixed-population-dilemma/) [Ebook](/resources/your-cell-count-is-a-safeguard/) Moxi GO II Moxi V Moxi Z 2026 ### Your Cell Count is a Safeguard The debris problem: Membrane fragments, aggregates, media residue, and lysed cell debris are present in virtually every biological preparation. How does your counting method distinguish a cell from a piece of debris? [Read Ebook](/resources/your-cell-count-is-a-safeguard/) [App Note](https://precisioncellsystems.com/wp-content/uploads/2026/02/Moxi-Applications-Compendium.pdf) Moxi GO II Moxi V Moxi Z 2026 ### Applications Compendium Scientists are concerned with speed, accuracy, and convenience, and those running the lab and industries are concerned with the cost typically associated with high-performing instruments. Our proprietary Coulter Principle-based system delivers on all three accounts, and is therefore a perfect fit for any cell biology benchtop. [Download App Note](https://precisioncellsystems.com/wp-content/uploads/2026/02/Moxi-Applications-Compendium.pdf) [Field Guide](/resources/05-suboptimal-resolution/) Moxi GO II Moxi V Moxi Z 2026 ### The Suboptimal Resolution Problem: Why Your Cell Populations Look Merged Using an aperture much larger than necessary reduces sizing resolution by creating smaller signal differences between cell sizes. Cell populations that should be distinguishable appear merged when the aperture is too large for the cells being measured. Target 15-40% of aperture diameter for optimal resolution. If you're counting lymphocytes on M+ cassettes because it works, you're sacrificing the sizing resolution that S+ cassettes would provide. [Read Field Guide](/resources/05-suboptimal-resolution/) [Field Guide](/resources/04-coincidence-artifact/) Moxi GO II Moxi V Moxi Z 2026 ### The Coincidence Artifact: When Two Cells Count as One Coincidence - multiple cells in the aperture simultaneously - causes two cells to be counted as one, corrupting both count and size data. Optimal aperture utilization means targeting 15-40% of aperture diameter so cells generate strong signals while avoiding coincidence artifacts. Match your cassette to your cell size, stay within concentration guidelines, and coincidence becomes a non-issue. [Read Field Guide](/resources/04-coincidence-artifact/) [Brochure](https://precisioncellsystems.com/wp-content/uploads/2025/12/Moxi_GO_II_Brochure.pdf) Moxi GO II 2025 ### Brochure - Moxi GO II [Download Brochure](https://precisioncellsystems.com/wp-content/uploads/2025/12/Moxi_GO_II_Brochure.pdf)